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| Savage syndrome ： ウィキペディア英語版 |
Gonadotropin-resistant ovary syndrome
Resistant ovary syndrome, previously known as Savage Syndrome, is a cause of ovarian failure that can lead to secondary amenorrhea. "Resistant ovaries" result from a functional disturbance of the gonadotrophin receptors in the ovarian follicles. It may be a cause of primary or secondary amenorrhoea and is resistant to exogenous gonadotrophin stimulation.
Diagnosis of this condition requires that the patient has a normal 46,XX karyotype, normal secondary sexual characteristics, elevated plasma FSH and LH - in the menopausal range - and that normal, multiple follicles are seen on ovarian biopsy.
Spontaneous reversal of the receptor blockade may occur.〔http://www.acfs2000.com/basic_services/premature-ovarian-failure-pof.html〕
==References==
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
■ウィキペディアで「Gonadotropin-resistant ovary syndrome」の詳細全文を読む
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